Casablaca Movie Review essays

Casablaca Movie Review essays Casablanca is in my opinion one of the best movies of all time, bringing together excellent actors, creative artists and a perfect story. Since so many reviews and studies have been done on Casablanca it is hard to approach it with a genuine touch so in a way this is a study done with all those point of views used as a source and blended together. Casablanca was awarded three Academy awards in 1943 for Best Screenplay, Best Picture and Best Director thus recognizing the qualities that Casablanca possesses. The only regret about this film in regards to the awards and recognition it received is that almost no acknowledgement was made of Ingrid Bergman exquisite acting. The review of the professional critic I am including in this study is of Tim Dirks one of the most renown critics: The classic and much-loved romantic melodrama Casablanca (1942), always found on top-ten lists of films, is a masterful tale of two men vying for the same woman's love in a love triangle. The story of political and romantic espionage is set against the backdrop of the conflict between democracy and totalitarianism. With rich and smoky atmosphere, anti-Nazi propaganda, Max Steiner's superb musical score, suspense, unforgettable characters and memorable lines of dialogue (e.g., "Here's lookin' at you, kid", and the inaccurately-quoted "Play it again, Sam"), it is one of the most popular, magical (and flawless) films of all time - focused on the themes of lost love, honor and duty, self-sacrifice and romance within a chaotic world. Woody Allen's Play It Again, Sam (1972) paid reverential homage to the film, as have the lesser films Cabo Blanco (1981) and Barb Wire (1996), and the animated Bugs Bunny short Carrotblanca (1995). Dirks, Tim Casablanca (1942), A review by Tim Dirks. Michael Curtiz; of Hungarian origin and recent immigrant, was the Director and one of the member of the creative team responsible for the success of...

Analysis Of Ancient Egyptian History History Essay

Analysis Of Ancient Egyptian History History Essay Ancient Egypt was known as the’Cradle of Civilization’. Egyptian civilization is a gift of the Nile River that flows from the northern part of Egypt to the Mediterranean Sea. The river nile was the longest river that located in the Northern Africa. According to historian, Egypt was the second and the oldest civilization in the world that was formed about 3000 B.C.E. The Egypt remains a very interesting history in terms of culture, religion, agriculture, powerful government, their economy, construction of buildings like the pyramids and so forth. Historically, Egypt is an old civilization that ruled by the 30 dynasty of pharaohs in 3100 B.C.E and 332 B.C.E , which it has been divided into the three most major time periods in Egypt, those kingdoms were; the Old kingdom, Middle kingdom and New kingdom. The history of timeline of Ancient Egypt Historians also have divided the time period of ancient Egyptian history to some of the period. The following periods were: Prehist oric ( – 3100 BCE), Early Dynastic Period ( 3000 – 2686), Old Kingdom ( 3000 – 2890), First Intermediate Period (2181 -2055), Middle Kingdom (2055-1650), Second Intermediate Period (1650-1550), New Kingdom (1550 – 1069), Third Intermediate Period (1069 – 664) and Late Period (664 – 332) Pharaoh The King of Egypt was called as Pharaoh, which in other words, â€Å"greatest house†. Pharaoh had absolute power over Egypt and is fully entitled. In the reign of the pharaoh, the Egyptians believed in the existence of God, where the pharaoh considered as god. Pharaoh is not only a political leader that was exalted by the society of Egypt, but he is also regarded as a religious leader as well. Social Organization Position of women Women have a unique status in the Egyptian civilization as it has its own rights. Women role is very important ancient Egypt as the wife and mother, and also its position has been considered precious. In the royal fam ily, the ancient Egyptian women not only became the wife of a pharaoh, or a god, but will become the mother of the pharaoh. Pharaoh could have more than one wife. Religion and beliefs of ancient Egypt Ancient Egyptian civilization is known as a religious center, as evidenced by the discovery of monuments and temples of the religious nature of ancient Egyptian society and beliefs. The Egyptian believed that the world was dominated by many gods to determine life and death of a life, which was also called as trust in polytheism. Each of the Egyptian god often associated with the natural elements such as Re (sun god), Ra-Atum (God’s Heaven) and Amun (Wind God). The Egytian worship the ‘spirit’ where it is believed to help them obtaining the benefits and avoid misfortune or natural disaster. For instance, the Egyptian society worships ‘plant spirit’ to get a good crop. Pharaoh was deemed to be the descendants of God, and because of these, Pharaoh regarded as the great god and has the right to do anything for the Egyptian society. Ancient Egyptian society believes that there is life after death. For them, the person who died will live again in the hereafter. Thus, they preserve bodies (mummification) and build a huge pyramid to keep the mummy of the pharaoh. Pyramid is considered as a meditative spirit, used to store treasures, such as the property of the pharaoh. Food and furniture are also stored in the pyramids because they believed that by doing so the spirit will live in the hereafter.ListenRead phoneticallyListen

Leadership and control plan Assignment Example | Topics and Well Written Essays - 500 words

Leadership and control plan - Assignment Example The president of the firm is currently not delegating any responsibilities to its vice-presidents. A lot of changes have to occur at this company to turn things around. A new leadership plan has to be implemented to improve the employee morale at the firm. One of the first steps to show the employees that the firm cares about their professional development is to immediately implement a training and development plan. Each month all the employees of the firm should have the opportunity to receive at least an hour of training. The firm should have both required and voluntary training and development sessions. The managerial staff of the firm should receive advance training on leadership topics. Another way to improve leadership within the company is by adopting the use of delegating and empowerment. These two topics should be emphasized in the training and development efforts of the firm. Delegation can be defined as the process of giving power or work to someone else so that they are responsible for part of what they normally do (Theyagu). Leadership can also be enhanced at the company by the utilization of teamwork. Working in team units allows work ers to improve their communication skills and to work in a cohesive manner with their colleagues to achieve common goals. The control measures of the company are completely inadequate. The firm has a major weakness in its accounting department. The firm’s accounting department is understaffed and not performing adequately. The first step is for the firm to hire a consultant in accounting to perform an external auditing to ensure that the company is complying with the generally accepted accounting principles (GAAP). The external audit performed by this firm must be evaluated by the newly hired position of comptroller at the firm. Along with a comptroller the firm must hire two additional staff accountants with at least three years of experience in accounting. The newly form accounting

Apology versus Crito Essay Example | Topics and Well Written Essays - 1500 words

Apology versus Crito - Essay Example Apology versus Crito He questions politicians, poets and craftsmen and discovers that they in fact lacked proper knowledge. He challenges the people of Athens and proves that they are ignorant and foolish. He affirms that he is the wisest man because he knows that he knows nothing. His chief complainant is a man named â€Å"Meletus† (Apology) whom Socrates criticizes and questions him severely for calling him an atheist and blaming him for violating god made laws. Socrates claims strongly that he is not scared of the wrong accusations of the society and his life after death and because according to him it is unwise to fear death when you do not even knows what happens to the life after ones demise. Socrates calls Athens as â€Å"a lazy horse† (Apology) and compares himself to a gadfly who stings the people to provoke them. Socrates does not like politics as in his opinion his involvement in politics would have prevented him to serve for his people; lastly he defends himself and his sincere friends who stood by him through thick and thin, and praises his associates for loving him unconditionally. Moreover he favors death to imprisonment and exile, he thinks that â€Å"a life that is not examined is not worth living† so he would continue philosophizing even if his life is at stake. The â€Å"Apology† provides the most significant defenses of a truth-seeking life by Socrates. In his speech he contrasts himself with many well-known people and persuades that his philosophy and thinking is far better and different from others as he does not believe in just acquiring knowledge but rather clarifying ones judgment his philosophical views are entirely different from other philosophers, according to him, the

Social Questions and Answers Essay Example | Topics and Well Written Essays - 250 words - 1

Social Questions and Answers - Essay Example From this paper it i clear that the U.S. society would collapse due to the different cultures mixed together. Marx felt the Capitalism would fall a long time ago. Weber would feel that because the United States has differing opinions that it would fall, as would Durkheim. What each individual did not take into account was the American system is not rigid. It is flexible to change, so if something does not work the citizens can change it. The American culture grows and reinvents itself everyday. That is why it has lasted so long.This study outlines that Marx had a Conflict Theory. He believed that the workers would turn on the richer class in the capitalist society. Marx thought the poor people would revolt against the rich people. What he did not take into account is everybody has a fair chance to become rich, so the poor does not focus on the rich, but how to get rich. Durkheim used Functionalism. He believed that a society was a single essence. The society was driven on differences and similarities. The society can be more than just a single part, but the single parts make up the whole. Once again Durkheim thought America would collapse upon itself because of too many different parts. That is what makes it work though. Max Weber had the Interpretive Theory. He believed societies worked through intentional and unintentional actions. Weber thought that the interaction in America had too much conflict.

Ibandronate vs. Alendronate for Osteoporosis

Ibandronate vs. Alendronate for Osteoporosis Cost-Effectiveness of Ibandronate vs. Alendronate used in treatment of osteoporosis, in a specialized clinic in Tirana. Dr. Mirela Miraà §i1; Msc.Arlinda Demeti2; Prof.as Zamira Ylli3; Prof.Mira Zià §ishti3; Prof.As Suela Kellià §i1 Faculty of Pharmacy, University of Medicine, Tirana. Bioparafarmacia Franceze Neostyle Clinic Abstract: Osteoporosis is â€Å"a systemic skeletal disease with a high prevalence. Biphosphonates are medicaments which are chosen for their efficacy in reducing fracture incidence, increasing bone density and improving bone microarchitecture. The aim of the study is to evaluate the effectiveness of the drugs (ibandronate and alendronate) used in osteoporosis treatment, in post-menopausal women over the age of 50 years at a specialized clinic in Tirana; to calculate the annual cost of treatment of osteoporosis and to perform a cost effectiveness analyze. Methods: Retrospective. The patients were all female, in menopause or post menopause, with T-score -1 to -6, treated with alendronate or ibandronate. The effectiveness is calculated as the average percentage of change in bone mineral density (av. % of change in BMD) of year 2011 vs. 2010 baseline. The annual cost of the treatment of osteoporosis according to the protocols and the cost of the examination with DXA scan (dual x-ray absorptiometry) were calculated. Finally a comparison of the cost-effectiveness was performed. Conclusion:  Patients with osteoporosis treated with Ibandronate, at our clinic in Tirana, have an average change from baseline higher compared with patients treated with Alendronate, with statistically significant difference between them (Man Whitney U = 66.0, p The annual cost of the disease when treated with ibandronate is 1.3 times higher than the annual cost of treatment with alendronate. Ibandronate is more cost effective than all other alendronate . Introduction: Osteoporosis is â€Å"a systemic skeletal disease characterized by low bone mass and micro architectural deterioration of bone tissue, with a consequent increase in bone fragility and susceptibility to fractures† (1) The World Health Organization defines osteoporosis as â€Å"bone density 2.5 standard deviations (SDs) below the mean for young white adult women at lumbar spine, femoral neck or forearm†. (2) Osteoporosis leads to nearly 9million fractures each year worldwide and over 300,000patients with fragility fractures are registered in UK hospitals each year (British Orthopaedic Association, 2007).(3) Osteoporoza, à «shtà « njà « sà «mundje me njà « prevalencà « tà « lartà « edhe nà « Shqipà «ri (7.28% e popullatà «s dhe 9.6% tek femrat)4, e njà «jtà « me atà « tà « hasur pà «r astmà «n apo sà «mundjet e zemrà «s; †¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦.. Direct medical costs due to fragility fractures in UK healthcare economy were estimated at  £1.8billion in 2000, with the potential to increase to  £2.2billion by 2025 and the major part of these costs were related to hip fracture care. (5) The annual cost of osteoporosis and fractures in the US elderly was estimated at $16 billion(6) Osteoporosis is diagnosed by a T-score, which is the number of standard deviation (SD) that patient’s bone mineral density (BMD), measured using dualX-ray absorptiometry, differs from the mean BMD of 30-years old premenopausal women. Patients with T-score of between -1 and -2.5 SD are said to have osteoporosis.7,8 Biphosphonates are medicaments which are chosen for their efficacy in reducing fracture incidence, increasing bone density and improving bone microarchitecture.9-15 Top of Form Methods: Retrospective. The patients were all female, in menopause or post menopause, 50 years old or elder, with T-score -1 to -6, diagnosed for the 1rst time in 2010 (the 1rst BMD measurement), who have received treatment (alendronate or ibandronate) for 12 months and in 2011 have performed a 2nd BMD measurement. The effectiveness is calculated as the average percentage of change in bone mineral density (av.% of change in BMD) of year 2011 vs. 2010 baseline. It was calculated the annual cost of the treatment of osteoporosis according to the protocols: with once monthly 150 mg oral ibandronate plus supplements (calcium, vitamine D) and once weekly 70 mg alendronate (4 times per month) plus supplements (calcium, vitamine D). There are also included other direct costs such as the examination with DXA scan (dual x-ray absorptiometry) to determine the diagnosis and the medical visits. Finally a comparison of the cost-effectiveness will be performed. Statistical Analysis Data were analyzed with SPSS 20 statistical package. It is used the non-parametric Man Whitney U test to compare the continuous variables, Fisher Exact test was used to compare proportions between variables and the the Odds Ratio OR for assessing the association between variables. Point estimations are accompanied with interval estimation by 95 % CI. For continuous variables is presented the average, the standard deviation and the minimum and maximum values. The level of statistical significance is defined at ÃŽ ± ≠¤ 005. Statistical tests are two-sided.duhet te shihet gjuha e perdorur, a qendron ne anglisht? Results of the study In our study were included 70 patients who fulfill the inclusion criteria. 24 patients were treated with once monthly 150 mg oral ibandronate and 46 patients with once weekly 70 mg alendronate.There were not case of fracture among our patients. Table 1 compares the frequency of pathologies (osteopenia and osteoporosis) in two groups of patients treated with alendronat or ibandronat. Osteoporosis Osteopenia Ibandronate 14 10 Alendronate 18 28 OR= 1.3 95%CI 0.5 4.2 p=0.4 Your contribution will be used to improve translation quality and may be shown to users anonymously Contribute Close Thank you for your submission. Number of patients treated with alendronate is 1.3 times higher than the number of patients treated with ibandronate in the case of osteoporosis. (OR = 1.3, 95% CI 0.5-4.2, p = 0.4). Chart 1 Calculation of efficiency We have to calculate the average percentage of change of BMD (2011) to baseline (2010): Table2. In the group of Alandronate (N=46) we have found this data: Osteoporosis n=18 Osteopeni n= 28 M (SD) min max M (SD) min max Mann-Whitney U p T Score 2010 -3.2 (0.7) -4.6 -2.5 -1.9 (0.4) -2.4 -1.1 507.0 T Score 2011 -3.1 (0.8) -4.7 -2.2 -1.8 (0.6) -2.4 -1.1 515.5 Age, yrs 61.2 (8.0) 51.0 – 79.0 59.1 (7.8) 51.0 – 81.0 223.5 0.3 Height, m 1.5 (0.05) 1.4 – 1.6 1.5 (0.07) 1.4 – 1.7 304.5 0.3 Weight, kg 58.8 (8.3) 46.0 – 73.0 68.6 (11.1) 51.0 – 95.0 376.5 0.01 *Age-Group, yrs n (%) n (%) OR (95% CI) 50 -59 yrs 8 (17) 19 (41) 60 -69 yrs 7 (15.2) 6 (13.0) 1.6 0.4 – 6.7 0.4 >70 yrs 3 (7) 3 (7) 2.8 0.4 – 25.2 0.3 *Fisher exact test p=0.3 There are 46 patients treated with alendronate. 18 ( 39.1 %) (95% ; CI 29.7 52.1) of them suffer from osteoporosis and 28 ( 60.9 % ) (95 % CI 47.8 74.2) from osteopenia, with no statistically significant difference between them, p = 0.9 Grupmosha 60 – 69 vjeà § ka 1.6 herà « mà « tepà «r gjasa qà « tà « vuajnà « nga Osteoporoza sesa grupmosha 50-59 vjeà §, por pa ndryshim sinjifikant ndà «rmjet tyre (OR=1.6; 95%CI 0.4–6.7; p=0.4) Grupmosha >70 vjeà § ka 2.8 herà « mà « tepà «r gjasa qà « tà « vuajnà « nga osteoporoza sesa grupmosha 50-59 vjeà §, por pa ndryshim sinjifikant ndà «rmjet tyre (OR=2.8; 95%CI 0.4–25.2; p=0.3) Pacientet me Osteopeni kanà « peshà « mesatare mà « tà « lartà « krahasuar me pacientà «t me Osteoporozà «, me ndryshim statistikisht tà « rà «ndà «sishà «m ndà «rmjet tyre (Man Whitney U=376.5, p=0.01) Pacientà «t me Osteoporozà « kanà « tà « njà «jtà «n gjatà «si mesatare me pacientà «t me Osteopeni, pa ndryshim statistikisht tà « rà «ndesishà «m ndà «rmjet tyre (Man Whitney U=304.5, p=0.3). The change from baseline for Alendronate group The change from baseline is calculated: Table 3 Osteoporosis n=18 Osteopenia n= 28 M (SD) min max M (SD) min max Mann-Whitney U p The change from baseline 2.1 (4.5) -7.6 – 13.9 1.7 (6.2) -23 – 11.1 316.0 0.2 Patients with osteopenia have an average change from baseline higher compared with patients with osteoporosis, no statistically significant difference between them (Man Whitney U = 316.0, p = 0.2). Table 4. In the group of Ibandronate (N = 24) we have find this data: Osteoporosis n=14 Osteopeni n= 10 M (SD) min max M (SD) min max Mann-Whitney U p T Score 2010 -3.7 (0.7) -5.0 -2.7 -1.8 (0.3) -2.2 -1.4 140.0 T Score 2011 -3.2 (0.8) -4.4 -1.7 -1.5 (0.4) -2.1 -1.0 134.5 Age yrs 64.3 (7.3) 53.0 77.0 59.1 (5.0) 53.0 – 68.0 39.5 0.07 Height (m) 1.5 (0.05) 1.4 – 1.6 1.5 (0.06) 1.4 – 1.6 71.0 0.9 Weight 66.2 (10.9) 47.0 – 84.0 70.7 (7.1) 65.0 – 82.0 90.5 0.2 *Age-group, yrs n (%) n (%) OR (95% CI) 50 -59 yrs 3 (12.5) 6 (25.0) 60 -69 yrs 8 (33.3) 4 (16.7) 3.7 0.6 – 27.8 0.2 >70 yrs 3 (12.5) 0 13 0.5 – 33.0 0.03 *Fisher exact test p There are 24 patients treated with Ibandronate. 14 (58.3%), (95% CI 33.2-76.5) of them suffer from osteoporosis and 10 (43.7%), (95% CI 23.4-61.7) of osteopenia, no statistically significant difference between them, p = 0.9. Pacientà «t me Osteoporozà « kanà « njà « moshà « mesatare mà « tà « lartà « krahasuar me pacientà «t me Osteopeni, por pa ndryshim statistikisht tà « rà «ndà «sishà «m ndà «rmjet tyre (Man Whitney U=39.5, p=0.07). Pacientà «t me Osteoporozà « kanà « tà « njejtà «n gjatà «si mesatare me pacientet me Osteopeni, pa ndryshim statistikisht tà « rà «ndà «sishà «m ndermjet tyre (Man Whitney U=71.0, p=0.9) Grupmosha 60 – 69 vjeà § ka 3.7 herà « mà « tepà «r gjasa qà « tà « vuajà « nga Osteoporoza sesa grupmosha 50-59 vjeà §, por pa ndryshim sinjifikant ndà «rmjet tyre (OR=3.7; 95%CI 0.6–27.8; p=0.2). Grupmosha >70 vjeà § ka 13 herà « mà « tepà «r gjasa qà « tà « vuajà « nga osteoporoza sesa grupmosha 50-59 vjeà § me ndryshim sinjifikant ndà «rmjet tyre (OR=13; 95%CI 0.5–33.0; p=0.03). Pacientà «t me Osteopeni kanà « peshà « mesatare mà « tà « lartà « krahasuar me pacientà «t me Osteoporozà «, por pa ndryshim statistikisht tà « rà «ndà «sishà «m ndà «rmjet tyre (Man Whitney U=90.5, p=0.2) The change from baseline for Ibandronate group (N=24) The change from baseline is calculated: Table5 Osteoporosis n=14 Osteopenia n= 10 M (SD) min max M (SD) min max Mann-Whitney U p The change from baseline 7.3 (6.1) -0.5 – 17.3 3.3 (2.2) -1.3 – 6.3 43.0 0.1 Patients with osteoporosis have an average change from baseline higher compared with patients with osteopenia, no statistically significant difference between them (Man Whitney U = 43.0, p = 0.1) Comparison of change from baseline for patients with osteoporosis referring the two drugs. Table 6. Alendronate n=18 Ibandronate n= 14 M (SD) min max M (SD) min max Mann-Whitney U p The change from baseline 2.1 (4.5) -7.6 – 13.9 7.3 (6.1) -0.5 – 17.3 66.0 Chart 2. The change from baseline for patients with osteoporosis Pacientà «t me Osteoporozà « tà « mjekuar me medikamentin Ibandronat kanà « njà « ndryshim mesatar nga baseline mà « tà « lartà « krahasuar me pacientet e mjekuar me Alendronat, me ndryshim statistikisht tà « rà «ndesishà «m ndà «rmjet tyre (Man Whitney U=66.0, p Table 7. Percentages of the average change of BMD from baseline Total Osteoporosis Ostopenia Alendronate 1.83564848 2.081694 1.677476 Ibandronate 5.635355 7.27025 3.346503 Chart 3. Nga figura rezulton se efikasiteti i medikamentit ibandronat (5.6) à «shtà « dukshà «m mà « i lartà « se efikasiteti i medikamentit alendronat (1.8). Efikasiteti i medikamentit ibandronat tek pacientà «t me osteoporozà « (7.3) à «shtà « dukshà «m mà « i lartà « se efikasiteti i medikamentit alendronat (2.1). Efikasiteti i medikamentit ibandronat tek pacientà «t me osteoponi (3.3) à «shtà « mà « i lartà « se efikasiteti i medikamentit alendronat (1.7). Cost analysis We consider only direct costs such as: DXA scanner examinations, medical visits and medications costs (drugs and the supplements), according to a well-defined treatment protocol. In Albania, there is only one kind of ibandronate (only one brand) 150 mg / once a month, while there are lots of alendronate (different brands) 70 mg / 4 times per month, which we have called A1,A2,A3, A4,A5. We have calculated the costs of the only ibandronate and the costs of five types of alendronate, including the alendronate produced by a pharmaceuticals firm in the country, which has the lowest price in the market. In both cases the basic treatment is associated with calcium and vitamin D. Table 8 Annual Cost of treatment and cost of examination Nr Currency Quantity Cost Month Annual Costs 1 Diagnostics skaner DXA Lek1 1 4,000 4,000 Medical examination 1 1,000 1,000 2 Type of Alendronat 70mg A1 lek 4 3,410 12 40,920 A2 lek 4 2,093 12 25,116 A3 lek 4 3,301 12 39,612 A4 lek 4 4,102 12 49,224 A.5 (Albanian Product) lek 4 1,200 12 14,400 3 Ibandronat 150 mg lek 1 4,873 12 58,476 4 Calcium Carbonat 1000 mg + Colecalciferol 880 UI lek 30 1,019 12 12,228 Table 9 Cost of illness according the type of medications Type of Alendronat 1+2+4 Annual costs A1 lek 58,148 A2 lek 42,344 A3 lek 56,840 A4 lek 66,452 A5 lek 31,628 Type of Ibandronat 1+3+4 Annual costs I1 lek 75,704 The annual cost of the disease when treated with ibandronate is 2.4 times higher than the annual cost of treatment with alendronate the alendronate produced by a pharmaceuticals firm in the country, which has the lowest price in the market, respectivly 537[1] euro versus 226 euro per patient in alendronate group. Having all the annual costs and the efficiency for each drug, we can compare: Table 10 Name (Changes by baseline in %) Efficiency of alendronate 1.83565 Efficiency of ibandronate 5.63536 Table11 Type of treatment C/E Alendronate A1 31,677 A2 23,068 A3 30,965 A4 36,201 A5 17,230 Ibandronate 13,434 The analyse of cost per efficiency unit (Table 10) shows that in the case of ibandronate the value obtained is 13.434 units and in alendronate A1 case is 31.677 units. Discussion of results Patients with osteoporosis treated with Ibandronate, at our clinic in Tirana, have an average change from baseline higher compared with patients treated with Alendronate, with statistically significant difference between them (Man Whitney U = 66.0, p 16 The annual cost of the disease when treated with ibandronate is 1.3 times higher than the annual cost of treatment with alendronate A1 and 2.4 times higher than the annual cost of treatment with the alendronate produced by a pharmaceuticals firm in the country, which has the lowest price in the market. So as claimed, the cost for effectiveness unit is lower (about 2.3 times) in the case of ibandronate compared to alendronate A1. Well ibandronate results the most cost- effective. Ibandronate turns more cost effective than all other alendronate including the alendronate produced by a pharmaceuticals firm in the country, which has the lowest price in the market Literature Christiansen, C. (1993). Consensus development conference: diagnosis, prophylaxis,and treatment of osteoporosis. Am J Med 94:646–50. Kanis, J.A. (1994). Assessment of Fracture Risk and its Application to Screening forPostmenopausal Osteoporosis. Report of a WHO Study Group. Geneva: World HealthOrganization. Johnell O, Kanis JA (2006) An estimate of the worldwide prevalence and disability associated with osteoporotic fractures. Osteoporosis International 17: 1726–33. Dorina Ruco,(Dhjetor 2011): Osteoporoza nà « qytetin e Tiranà «s British Orthopaedic Association (2007).The care of patients with fragility fracture. Burge RT, Worley D, Johansen A, et al. The cost of osteoporotic fractures in the UK: projections for 2000–2020. Journal of Medical Economics 4: 51–52. Blume SW,Curtis JR Osteoporos Int.2011 Jun;22(6):1835-44. doi: 10.1007/s00198-010-1419-7. Epub 2010 Dec 17. Medical costs of osteoporosis in the elderly Medicare population. BMJ Group. Annual zoledronic acid for osteoporosis. Drug Ther Bull. 2008 Dec;46(12):93-6. Cummings SR, Melton LJ. Epidemiology and outcomes of osteoporotic fractures. Lancet 2002;359:1761e7. Delmas PD. Treatment of postmenopausal osteoporosis. Lancet 2002;359:2018e26. Hochberg MC, Ross PD, Black D, et al. Larger increases in bone mineral density during alendronate therapy are associated with a lower risk of new vertebral fractures in women with postmenopausal osteoporosis.Fracture Intervention Trial Research Group. Arthritis Rheum 1999;42:1246e54. Hochberg MC, Greenspan S, Wasnich RD, et al. Changes in bone density and turnover explain the reductions in incidence of nonvertebral fractures that occur during treatment with antiresorptive agents. J Clin Endocrinol Metab 2002;87:1586e92. Epstein S. The roles of bone mineral density, bone turnover, and other properties in reducing fracture risk during antiresorptive therapy. Mayo Clin Proc 2005;80:379e88. McClung MR, Wasnich RD, Recker R, et al. Oral daily ibandronateprevents bone loss in early postmenopausal women with osteoporosis.J Bone Miner Res 2004;19:11e8. Rosen CJ. Postmenopausal osteoporosis. N Engl J Med 2005;353: Miller PD,Epstein S,Sedarati F,Reginster JY Once-monthly oral ibandronate compared with weekly oral alendronate in postmenopausal osteoporosis: results from the head-to-head MOTION study. http://www.ncbi.nlm.nih.gov/pubmed/18042311

Religion and State Sovereignty :: social issues

Religion and State Sovereignty The influence of religion on humankind can be traced back to the first records of history. Religion has served as a pillar of strength to some and binding chains to others. There are vast amounts of information and anthropological studies revealing the interaction of religion and humankind. However, for the purposes of this paper, the time periods of study will be broken up into three sections. Each section will give a general description of how religion affected the institution of the state and its Sovereignty in a Euro-centric perspective. The first period is the early period, which will encompass from Christianity and the Roman Empire to the Medieval times (approx. 311 to 1100 A.D.). The second period will include the Renaissance, the Reformation to the Treaty of Westphalia (1101 to 1648 A.D.). The third and increment of history will range from 1649 to 1945 A.D. The date 311 A.D. marks the issuing of the "Edict of Toleration" for Christians. This date is important because it symbolizes "national" acceptance of Christianity, and planted its roots as a political institution. Later the Roman Empire on the verge of internal collapse acknowledged the importance of Christianity and used it to hold together the remnants of it former self. This adoption of Christianity took form and eventually became the Catholic church.The church became intermingled with politics and became a strong entity. The policies delivered from the church had more authority than the local rulers and magistrates of the developing feudal system. For example, St. Augustine wrote about war and what justified its enactment against fellow men. This policy was followed and adhered to for hundreds of yea rs after St. Augustine wrote it. Another example, is the use of the Bible as a guideline for establishing governing systems. Scripture portrayed God as choosing the king of the people. The pope, being God's "representative" was then given the authority to crown the king. This crowning process gave the pope large influence in the political arena. This ritual continued for a number of centuries. The Crusades, which occurred around 1100 A.D., played a crucial role in challenging the church's authority. The pope identifying the spread of Islam as evil requested all of Europe embark on a "Crusade" to defeat the infidels. As the battles were fought, great treasures were found in the form of books and knowledge. These books were crude translations of old Greek texts, containing information which would eventually produce the waning of Church authority in the future.